The present study was undertaken to document operative mortality and morbidity and cumulative survival in patients who underwent Whipple's operation due to periampullary cancer and benign lesions including trauma from january 1980 throught April
1991.
Patients fell one of six categories based upon pathologic diagnosis; adenocarcinoma at the head of the pancreas (n=9), carcinoma of the distal common bile duct (n=11), adenocarcinoma of the ampulla of vater (n=9), duodenal carcinoma (n=9), other
cancers
not considered part of the periampullary region (n=3), and benign disease (n=12). Of the 19 patients alive at the time of this study, ten were patients with benign disease. Eight of the 53 patients were lost to follow-up.
In malignant group, overall mean survival time was 23.7 months until present study: 1 year survival rate, 75%, 2 year survival rate, 62.5%, 3 year survival rate, 38.5%, and 5 year survival rate, 25%.
Postoperative death was developed in 6 (11.3%) of 53 patients: malignant group, 4 patients; non-maligant group, 2 patients. Its causes were sepsis (n=2), postoperative bleeding (n=2), hepatorenal syndrome (n=1), and long-standing anesthesia
(n=1).
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